ZHEWITRA 40

What is ZHEWITRA 40?

ZHEWITRA 40 is a drug for the symptomatic treatment of erectile dysfunction in adult men. It contains vardenafil, which belongs to phosphodiesterase type 5 inhibitors, abbreviated as PDE-5. The product helps to achieve and maintain an erection sufficient for sexual intercourse, but acts only in the presence of sexual stimulation. The drug does not increase sexual desire and does not eliminate psychological or organic causes of erectile dysfunction.

ZHEWITRA 40 is available in the form of tablets for oral administration and contains 40 mg of vardenafil. This is a high dosage that exceeds the usual maximum recommended daily dose of vardenafil of 20 mg, so taking a whole tablet on your own can be dangerous. The choice of dose should be based on the state of the cardiovascular system, concomitant diseases and the list of other medications. Consultation with a doctor is mandatory before use.

The manufacturer of ZHEWITRA 40 is the pharmaceutical company Sunrise Remedies. The drug is positioned as a generic product based on vardenafil, but its registration status and legality of sale must be checked in official sources of Ukraine. The quality, composition and authenticity of tablets depend on the origin of the goods and compliance with storage rules. You should not buy medicines from unverified sellers or use packaging without proper labeling.

What is ZHEWITRA 40 prescribed for?

The main indication is erectile dysfunction — the recurrent inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. Vardenafil can be used for vascular, metabolic, neurological or mixed disorders after a medical examination. The doctor also assesses the potential impact of diabetes mellitus, arterial hypertension, obesity and the drugs taken. A single unsuccessful sexual intercourse by itself does not always indicate a disease.

ZHEWITRA 40 is not a means for permanent increase in potency and is not intended for men without erectile dysfunction. The drug does not treat infertility, premature ejaculation, low libido or testosterone deficiency. If the problem is related to anxiety, depression or relationship conflicts, consultation with a psychotherapist or sexologist may be required. Drug support does not replace diagnostics of the underlying cause of the disorder.

The 40 mg dosage is not considered a standard starting dose and should not be used simply because a lower dose seemed insufficiently effective. The lack of result may be due to incorrect timing of administration, fatty foods, insufficient stimulation or severe underlying disease. Unauthorized dose increase increases the risk of a drop in blood pressure and other adverse reactions. The optimal regimen is determined by the doctor after assessing the benefits and risks.

Composition and active components of ZHEWITRA 40

The active component of ZHEWITRA 40 is vardenafil at a dose of 40 mg, usually presented in the form of the corresponding salt. It temporarily inhibits the PDE-5 enzyme, due to which cyclic guanosine monophosphate accumulates in the cavernous bodies of the penis. This substance promotes relaxation of smooth muscles and increased blood filling during sexual stimulation. Without the natural release of nitric oxide, the drug does not cause an erection automatically.

Excipients form the tablet, ensure its strength, stability, coloring and disintegration in the digestive tract. Their exact list must be checked in the instructions for the specific packaging, as the composition of the shell and excipients may differ. Excipients do not treat erectile dysfunction, but may be important in case of allergies or intolerance to individual sugars. In the presence of such conditions, the composition should be discussed with a doctor or pharmacist.

Dosage of ZHEWITRA 40

The generally accepted starting dose of vardenafil for most adult men is 10 mg approximately 25–60 minutes before sexual activity. Depending on the efficacy and tolerability, the doctor may reduce it to 5 mg or increase it to 20 mg. The maximum recommended frequency is once a day, and the standard maximum dose is 20 mg. Therefore, a ZHEWITRA 40 tablet contains an amount of vardenafil that exceeds the usual daily limit.

Taking 40 mg of vardenafil without direct prescription and supervision of a doctor is not recommended. Splitting the tablet is possible only when it is provided for by its design and official instructions, since the absence of a score line does not guarantee an even distribution of the active substance. The product is used as needed, and not as a self-prescribed daily course. The duration of therapy and the need for re-examination are determined individually.

Dose adjustment may be required for elderly men, patients with impaired liver function or those taking drugs that slow down the breakdown of vardenafil. In severe hepatic impairment, use may be contraindicated or insufficiently studied. Kidney disease, unstable blood pressure and cardiac pathologies also require separate assessment. The individual reaction of the body differs, so someone else's treatment regimen cannot be considered safe.

How to take ZHEWITRA 40 correctly?

The tablet is swallowed with water at the time recommended by the doctor before anticipated sexual activity. The drug can be taken regardless of food, but very fatty food can delay the onset of its action. Sexual stimulation is required for the effect, and the duration of the response does not mean a continuous erection. Vardenafil must not be combined with other drugs for the treatment of erectile dysfunction.

Since ZHEWITRA 40 is used as needed, the concept of a missed dose is usually irrelevant. Do not take a double amount of the drug or repeat the intake within the same day if the result was insufficient. Before treatment, it is necessary to inform the doctor about all prescription and over-the-counter drugs, supplements and cardiovascular diseases. The appearance of chest pain during sexual activity requires its termination and immediate medical attention.

Side effects of ZHEWITRA 40

Common adverse reactions of vardenafil include headache, flushing, nasal congestion, dizziness and dyspepsia, i.e. discomfort in the upper abdomen. Nausea, palpitations, back pain and temporary changes in visual perception are possible. A high dose may increase the frequency and severity of side effects. The body's reaction is always individual and depends on concomitant diseases and interactions.

Uncommonly, a decrease in blood pressure, fainting, tinnitus, shortness of breath, rash or swelling are observed. Rare but dangerous conditions include priapism — a painful erection lasting more than four hours, sudden loss of vision or hearing, severe allergic reaction and cardiac complications. For such symptoms, emergency medical assistance is required. In case of persistent or severe side effects, further use is discontinued until consultation with a doctor.

Contraindications of ZHEWITRA 40

Vardenafil is contraindicated in case of allergy to the active substance or excipients, as well as with simultaneous use of nitrates or nitric oxide donors. The combination with riociguat is dangerous due to the risk of a critical decrease in blood pressure. The drug is not used if sexual activity is not recommended due to a severe or unstable heart condition. Contraindications or grounds for special caution may include recent myocardial infarction or stroke, pronounced hypotension and severe hepatic impairment.

Caution is required in case of anatomical deformation of the penis, predisposition to priapism, peptic ulcer disease, bleeding disorders and hereditary retinal diseases. Vardenafil can affect heart rhythm, so patients with a prolonged QT interval or appropriate antiarrhythmic therapy need a doctor's evaluation. ZHEWITRA 40 is not intended for women, including during pregnancy or breastfeeding, and persons under 18 years of age. In old age, treatment is started carefully, taking into account concomitant diseases and increased sensitivity to the drug.

Interaction of ZHEWITRA 40 with other medicines and alcohol

Nitrates, riociguat and some other vasodilators are incompatible with vardenafil due to a dangerous drop in blood pressure. Alpha-blockers used for prostate hyperplasia or hypertension require a stable regimen and selection of the minimum dose. Vardenafil levels can be significantly increased by certain antifungal drugs, macrolide antibiotics and drugs for the treatment of viral infections. Grapefruit and grapefruit juice can also alter the metabolism of the drug, so they are best avoided.

Excessive alcohol consumption worsens erection and increases dizziness, weakness and low blood pressure. It is safest to avoid alcohol or limit its amount after agreement with a doctor. If visual impairment, dizziness or drowsiness occur after administration, you should not drive vehicles or operate machinery. Until the individual reaction of the body is clarified, activities requiring rapid reaction and concentration should be avoided.

Where to buy ZHEWITRA 40 in Ukraine

Before buying ZHEWITRA 40 in Ukraine, it is necessary to check the state registration of the drug, prescription requirements and the reputation of the pharmacy. Purchase is possible only through legal pharmacies or their official ordering and delivery services, if the product is approved for circulation. The packaging must have a batch number, expiration date, manufacturer's data, instructions and intact labeling. A suspiciously low price, sale by the piece without packaging or the promise of a guaranteed effect may indicate falsification.

ZHEWITRA 40 should be stored in its original packaging, in a dry place inaccessible to children, at the temperature specified by the manufacturer. Do not use tablets after the expiration date, in case of damage to the blister or change in their appearance. Delivery conditions must protect the drug from moisture, overheating and significant temperature fluctuations. Consultation with a doctor is mandatory before use, especially given the high dosage of 40 mg and the possibility of serious drug interactions.