DELGRA FXT

What is DELGRA FXT?

DELGRA FXT is a combination product for men designed to treat erectile dysfunction and premature ejaculation. The drug combines sildenafil and fluoxetine, thereby affecting both the mechanism of erection and the neurotransmitter regulation of ejaculation. DELGRA FXT is available in the form of tablets for oral administration. Before starting treatment, a doctor's consultation is required, as both active components have clinically significant contraindications and drug interactions.

Pharmacologically, sildenafil is a phosphodiesterase type 5 inhibitor, abbreviated as PDE-5, and fluoxetine is a selective serotonin reuptake inhibitor. This combination is sometimes considered for men who simultaneously experience insufficient hardness or duration of erection and difficulty controlling ejaculation. At the same time, DELGRA FXT is not a hormonal agent, an aphrodisiac, or a drug that automatically increases sexual desire. Sildenafil requires sexual stimulation to work.

Delta Enterprises is specified as the manufacturer of DELGRA FXT. Before purchasing, it is important to check the integrity of the packaging, labeling, batch number, expiration date, and the availability of information regarding the legal circulation of the drug in Ukraine. The combination of sildenafil 100 mg and fluoxetine 60 mg contains high doses of active substances and is not suitable for every patient. Self-medication, especially in the presence of cardiovascular diseases or while taking antidepressants, can be dangerous.

What is DELGRA FXT prescribed for?

The primary possible indication is erectile dysfunction — the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. Sildenafil improves blood flow to the corpora cavernosa of the penis in response to sexual stimulation. It does not eliminate all causes of erectile dysfunction, so the patient may need an evaluation of glucose levels, hormonal status, and cardiovascular health. Psychological factors, stress, smoking, and certain medications can also impair sexual function.

The second possible indication is premature ejaculation, when ejaculation regularly occurs sooner than desired, control over it is limited, and the situation causes significant distress. Fluoxetine increases serotonergic activity in the central nervous system, which may increase the time to ejaculation in some men. However, fluoxetine is not a drug that should be taken uncontrollably only before sexual contact. The dosing regimen is determined by a doctor after evaluating symptoms, psycho-emotional state, and concomitant therapy.

DELGRA FXT may be considered for a combination of two sexual disorders, but only after both conditions have been confirmed. Occasional failure during sexual intercourse does not always indicate a disease and is not an automatic reason for medical treatment. The doctor must rule out depression, anxiety disorder, prostatitis, endocrine disorders, and side effects of other medications. Individual body responses vary, so the efficacy and tolerability of DELGRA FXT cannot be guaranteed in advance.

Composition and active components of DELGRA FXT

The declared composition of DELGRA FXT contains sildenafil 100 mg and fluoxetine 60 mg in one tablet. Sildenafil inhibits PDE-5, which enhances the action of cyclic guanosine monophosphate and relaxes the smooth muscles of the penile blood vessels. This promotes blood flow and the formation of an erection in the presence of sexual stimulation. Without arousal, the drug usually does not cause a physiologically complete erection.

Fluoxetine reduces the reuptake of serotonin by nerve cells, increasing its availability in synapses — the sites of nerve signal transmission. This mechanism can delay the ejaculatory reflex, but the effect and the time of its development are individual. Fluoxetine has a long half-life, so its action and interactions may persist after discontinuation. Excipients form the tablet, ensuring its stability and dissolution; the exact list should be checked in the official instructions of the specific package, especially in case of allergies.

Dosage of DELGRA FXT

Due to the fixed combination of high doses, DELGRA FXT should not be used under a universal scheme without medical prescription. For sildenafil, the typical starting dose for erectile dysfunction is often lower than 100 mg, while the fluoxetine regimen depends on the indication, concomitant diseases, and prior treatment. Splitting the tablet on your own to adjust the dosage is only permissible when directly allowed by the instructions and the tablet has a corresponding score line. Taking more than one dose within a 24-hour period is dangerous.

The duration of use is determined by a doctor after evaluating the results and side effects. Fluoxetine should not be started, changed, or discontinued abruptly without consultation, especially if the patient is already receiving psychotropic drugs. A dose reduction or the choice of separate medications may be necessary for elderly men, patients with impaired liver or kidney function, and individuals taking CYP3A4 inhibitors. If the prescribed dose is poorly tolerated, repeated intake before consulting a doctor is not recommended.

How to take DELGRA FXT correctly?

The tablet is swallowed whole with a sufficient amount of water in accordance with the doctor's personal scheme. Fatty or very high-calorie food can delay the absorption of sildenafil and postpone the expected effect. Grapefruit and grapefruit juice can alter the concentration of sildenafil in the blood, so they are best avoided. The timing of administration relative to sexual contact and the necessity of regular use of fluoxetine must be determined by a specialist, not by advertising recommendations.

If the doctor has prescribed a regular regimen and a dose is missed, there is no need to double the next one. With an episodic regimen, a missed dose is not compensated for with extra tablets. Do not combine DELGRA FXT with other sildenafil preparations, potency medications, or antidepressants without a doctor's permission. Before taking, you must inform your specialist about all prescription and over-the-counter medications, herbal supplements, and psychoactive substances.

Side effects of DELGRA FXT

Common adverse reactions may include headache, facial flushing, nasal congestion, heartburn, nausea, diarrhea, dizziness, and sleep disturbances. Sometimes anxiety, tremors, sweating, fatigue, decreased libido, delayed orgasm, or other sexual dysfunctions occur. Sildenafil can cause temporary changes in color vision, blurred vision, or increased sensitivity to light. Severe or persistent symptoms require medical consultation.

Immediate medical attention is required for chest pain, fainting, seizures, sudden loss of vision or hearing, a severe allergic reaction, or an erection lasting more than four hours. A dangerous complication of fluoxetine is serotonin syndrome, signs of which may include agitation, confusion, fever, heavy sweating, tremors, muscle rigidity, and rapid heart rate. At the start of antidepressant therapy, sudden mood changes or suicidal thoughts are possible, requiring urgent medical help. The body's reaction is individual, and the absence of side effects after the first tablet does not guarantee the safety of subsequent doses.

Contraindications of DELGRA FXT

DELGRA FXT is contraindicated in case of allergy to its components, simultaneous use of nitrates or nitric oxide donors, as well as the guanylate cyclase stimulator riociguat. Such combinations can cause a critical drop in blood pressure. Fluoxetine must not be combined with monoamine oxidase inhibitors; intervals established by a doctor are required between these drugs due to the risk of serotonin syndrome. Contraindications or reasons for extreme caution include severe heart disease, unstable angina, recent heart attack or stroke, severe hypotension, and certain hereditary retinal diseases.

Caution is required in patients with anatomical deformation of the penis, predisposition to priapism, peptic ulcer disease, bleeding disorders, epilepsy, bipolar disorder, glaucoma, diabetes mellitus, and impaired liver or kidney function. DELGRA FXT is not intended for children, adolescents, and women, so its use during pregnancy or breastfeeding is not provided for. Elderly men may require a lower dose due to slower elimination of active substances and a higher probability of interactions. A doctor's consultation with an assessment of the cardiovascular risk of sexual activity is mandatory before use.

Interaction of DELGRA FXT with other drugs and alcohol

The most dangerous interaction is that of sildenafil with nitroglycerin and other nitrates, and fluoxetine with monoamine oxidase inhibitors, other serotonergic agents, tramadol, lithium, and St. John's wort. Alpha-blockers and blood pressure medications can increase hypotension, while some antifungal agents, antibiotics, and antiviral drugs can increase the concentration of sildenafil. Fluoxetine can interact with anticoagulants, antiplatelet agents, and nonsteroidal anti-inflammatory drugs, increasing the risk of bleeding. A complete list of medications must be provided to the doctor before starting therapy.

Alcohol can increase dizziness, drowsiness, drop in blood pressure, and sexual dysfunction, so it is recommended to avoid it. Until the individual reaction is established, one should not drive, work at heights, or operate dangerous machinery. Special caution is required if vision impairment, slowed reaction times, or instability occur after intake. Combining DELGRA FXT with recreational nitrates and other psychoactive substances poses a serious threat to health.

Where to buy DELGRA FXT in Ukraine

You should buy DELGRA FXT in Ukraine only in a licensed pharmacy or through an official pharmacy service, provided the drug is approved for circulation and available according to current dispensing rules. Before ordering, it is worth clarifying the registration status, the manufacturer Delta Enterprises, the composition, terms of sale, and the possibility of obtaining a pharmaceutical consultation. A suspiciously low price, lack of instructions, damaged packaging, or sales without proper labeling may indicate a counterfeit. Delivery must ensure protection of the packaging from moisture, overheating, and mechanical damage.

Store DELGRA FXT in its original packaging, in a dry place inaccessible to children, at the temperature specified in the official instructions. Do not use the tablets after the expiration date or if there is a change in their color, odor, or integrity. Ordering online does not replace a medical examination, and consulting a doctor before use is mandatory. The information provided is for reference purposes only and is not a personal prescription, as efficacy and safety depend on the individual reaction of the body.