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What is STENDRA?

STENDRA is a prescription medication for the treatment of erectile dysfunction in adult men. Erectile dysfunction means the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. The drug belongs to the pharmacological group of selective phosphodiesterase type 5 inhibitors. It works only in the presence of sexual stimulation and does not cause an erection automatically.

STENDRA is available in the form of oral tablets with various strengths of the active ingredient, most commonly 50, 100, or 200 mg of avanafil. Specific dosages, tablet appearance, and packaging configurations may vary depending on the country of supply and registration status. Manufacturer information must be verified on the original packaging and in the official instructions, as the manufacturer is not specified in the request. The medication should only be purchased from licensed pharmacies.

A feature of avanafil is its relatively rapid onset of pharmacological action, but the actual response time depends on the dose, food intake, and individual characteristics of the body. STENDRA does not increase sexual desire, does not treat infertility, and does not protect against sexually transmitted infections. The drug also does not eliminate the root cause of erectile dysfunction if it is associated with cardiovascular, endocrine, or neurological diseases. Prior to the first intake, a doctor's consultation with an assessment of the safety of sexual activity is mandatory.

What is STENDRA prescribed for?

The primary indication for the use of STENDRA is erectile dysfunction in adult men. The medication can help achieve an erection in response to sexual stimulation and maintain it during intercourse. It is prescribed for disorders of vascular, psychogenic, or mixed origin after a medical examination. Effectiveness may vary depending on the severity of the condition and coexisting diseases.

STENDRA may be considered by a physician for erectile disorders associated with diabetes mellitus, arterial hypertension, or other risk factors, provided there are no contraindications. At the same time, the medication does not replace the treatment of the underlying disease and lifestyle modification. Sexual stimulation is a necessary condition, as without the natural release of nitric oxide, avanafil does not provide the desired effect. Increasing the dose on one's own in case of an insufficient response is dangerous.

The drug is not intended to increase sexual stamina in men without diagnosed erectile dysfunction. It is not used as an aphrodisiac and does not directly affect testosterone levels. Before starting treatment, it is advisable to identify the possible causes of erectile dysfunction, including the side effects of other medications or psychological factors. The decision to prescribe is made by a doctor after evaluating the state of the heart, blood vessels, and general health.

Composition and active ingredients of STENDRA

The active substance of STENDRA is avanafil in the dose indicated on the package. It selectively inhibits phosphodiesterase type 5, an enzyme that breaks down cyclic guanosine monophosphate. Increasing the level of this compound promotes smooth muscle relaxation and increased blood flow to the corpus cavernosum of the penis. The mechanism is realized primarily during sexual arousal.

Excipients form the tablet, ensure its stability, disintegration, and proper release of avanafil, but do not treat erectile dysfunction. Their exact list should be checked in the instructions for the specific package, especially in case of allergies or intolerance to individual substances. The composition may include fillers, binders, glidants, and a coating. If hypersensitivity is suspected, use should be discontinued and medical assistance sought.

Dosage of STENDRA

The usually recommended starting dose for an adult man is 100 mg approximately 15 to 30 minutes before anticipated sexual activity. Depending on efficacy and tolerability, the doctor may decrease the dose to 50 mg or increase it to the maximum single dose of 200 mg. STENDRA should not be taken more than once a day. The lowest effective dose helps reduce the risk of adverse reactions.

The drug is used as needed, rather than necessarily as a continuous course. The duration of treatment is determined individually with periodic evaluation of efficacy, tolerability, and relevance of therapy. Dose adjustment may be required in case of coexisting diseases or the simultaneous use of drugs that affect the metabolism of avanafil. For patients with hepatic or renal impairment, the regimen is established by a physician.

How to take STENDRA correctly?

The STENDRA tablet is swallowed whole with a sufficient amount of water. The drug can be taken with or without food, but a high-fat and heavy meal can delay the onset of action. The time of administration depends on the prescribed dose and the recommendations of the official instructions. Sexual arousal is required for the effect to appear.

Since STENDRA is used as needed, the concept of a missed dose generally does not apply to this therapy. Do not take a double amount of tablets or repeat the dose within the same day if the effect was insufficient. Overdose can worsen headache, flushing, dizziness, decreased blood pressure, and other adverse reactions. In case of accidental overdose, it is necessary to consult a doctor.

Before taking STENDRA, a doctor's consultation is required, especially in the presence of chest pain, fainting, heart disease, or unstable blood pressure. The drug must not be combined with other treatments for erectile dysfunction. The individual response of the body may vary even with the same dosage. The absence of effect after several correctly performed attempts requires a medical review of treatment, rather than an independent dose increase.

Side effects of STENDRA

Common adverse reactions include headache, facial flushing and a feeling of warmth, as well as nasal congestion. Dizziness, back discomfort, indigestion, or palpitations are possible. Usually, these manifestations are mild to moderate and resolve on their own. If the symptoms are severe or recurrent, it is necessary to discuss a dose reduction or alternative therapy with a doctor.

Uncommonly, decreased blood pressure, weakness, nausea, or changes in vision may occur. Rare but dangerous conditions include a prolonged, painful erection lasting more than four hours, sudden loss of vision or hearing, and a severe allergic reaction. In case of chest pain, fainting, shortness of breath, or neurological symptoms, emergency medical assistance is required. Healthcare professionals should be informed of exactly when the last STENDRA tablet was taken.

Contraindications of STENDRA

Combining STENDRA with nitrates and nitric oxide donors is absolutely contraindicated due to the risk of a dangerous drop in blood pressure. The drug is not used in case of allergy to avanafil or excipients, as well as together with riociguat. Contraindications may include severe cardiovascular conditions in which sexual activity is inadvisable, recent myocardial infarction or stroke, unstable angina, and uncontrolled blood pressure disorders. Exact time limits and criteria are determined by the official instructions and the doctor.

Caution is required in case of anatomical deformation of the penis, predisposition to priapism, peptic ulcer disease, bleeding disorders, severe liver or kidney disease. STENDRA is not intended for women, so its use during pregnancy and breastfeeding is not provided for. The drug is not used in children and adolescents under 18 years of age. For elderly patients, the dose is selected taking into account general condition, concomitant medications, and cardiovascular risk.

Interaction of STENDRA with other drugs and alcohol

STENDRA is incompatible with nitrates, and combination with alpha-blockers and antihypertensive drugs can further lower blood pressure. Strong inhibitors of the CYP3A4 enzyme, including certain antifungal, antiviral, and antibacterial drugs, can significantly increase the concentration of avanafil and may be contraindicated. When using moderate inhibitors of this enzyme, the doctor adjusts the dose and the interval between doses. It is necessary to inform the specialist about all prescription and over-the-counter medicines, herbal remedies, and dietary supplements.

Excessive consumption of alcohol together with STENDRA increases the risk of dizziness, rapid heartbeat, orthostatic hypotension, and fainting. Alcohol can also independently impair erection, so its amount should be limited as much as possible. If dizziness, visual impairment, or weakness occur after taking the tablet, driving and operating machinery is prohibited. Returning to potentially hazardous activities is allowed only after assessing the individual response of the body.

Where to buy STENDRA in Ukraine

STENDRA can be purchased in Ukraine subject to availability in licensed brick-and-mortar or online pharmacies and in accordance with current prescription drug regulations. Before ordering, you should check the registration status, manufacturer, dosage, package integrity, batch number, and expiration date. Delivery must be carried out by a pharmacy service in compliance with appropriate transport conditions, and offers of questionable origin should be avoided due to the risk of falsification. Tablets must be stored in their original packaging, in a dry place inaccessible to children, and at the temperature specified in the instructions.

The availability and price of STENDRA may vary depending on the region, dosage, and pharmacy chain. You should not buy the drug from hands, through unverified advertisements, or without Ukrainian labeling and proper documentation. Before purchasing and taking, it is necessary to consult a doctor, as erectile dysfunction is sometimes an early sign of cardiovascular disease. This description is for informational purposes and does not replace official instructions, diagnosis, and individual medical prescription.